Faith and nature are entwined in this itinerary, which will surely be understood by anyone who follows this walk, leaving from Eremo di Montecasale. History tells us that this place was made famous by St. Francis of Assisi, whose presence here is linked to the story of two thieves, whose skulls are still preserved inside the ancient convent.

The Montecasale castle was destroyed in the 12th century, but in testimony to its strategic importance, it continued to be used as a home and a hospital for vagrants managed by Benedictine monks. The place was donated in 1212 to San Francesco. In 1224 he made his last visit to this area, whilst journeying from La Verna to Assisi. Montecasale has also given hospitality to Saint Antonio and Saint Bonaventura di Bagnoregio.

From the convent, take path 6A, which goes into the wood and rises until it reaches a house called 'Vesina'. Passing this old house, you go down until you reach 'Bucchio' (700m) and then you go up again until you get to 'Pischiano'. (748m) Here you will find path 6 (which comes from the village of La Montagna),  turn right on this path towards the south west until you reach path 4. From here and leaving behind path 6 you will climb steeply until you reach the ridge path 00 in the place called 'Poggio i Tre Termini' (1173m). From here, proceed North, walking along the gently undulating Apennine crest to the border with Marche until you reach M.Maggiore/Sbocco Bucine (1330m).

From here you enter the Nature Reserve 'Alpe della Luna'. This nature reserve is part of the  Apennines between Badia Telalda and Sansepolcro.  Alpe della Luna contains the watershed between the Upper Valley of the Tevere that flows towards the Tyrrhenian and the Marecchia River that flows to the Adriatic. In this heavily wooded area, there are many varieties of trees. You can also find some pretty meadows and ancient hamlets containing numerous scattered rural cottages, (some of which date back to the 13th century); testimony to a past when The Alpe della Luna was much more populated than today. Many of the old rural buildings, now  totally overgrown, played a part in the partisan resistance, acting as refuges and meeting places. Many years ago flocks of sheep would pass through this land on their way to Maremma.

Walking along path GAE 00 you arrive at Ripa della Luna where you can admire a splendid panoramic view of the whole of the Valmarecchia. After enjoying this view proceed towards Monte dei Frati (1453m) where you can refill your water containers from the two springs. The walk continues along path 00, passing Poggio delle coste, Col del Pegli (spring), Poggio dei Piani, Monte Verde (spring) until you arrive at Passo di Via Maggio (983m), where there is a restaurant / bar. From here go right along path 2, going down towards the Eremo of Cerbaiolo. After 20 minutes you arrive at  'le Camerelle', (spring) and from here you travel along the border of the Natural reserve of Montalto in which there are numerous and interesting natural woods.  The walk finishes at Eremo di Cerbaiolo, whose origins date right back to the 8th century. In 722 Tedaldo,  (who was Lord of Tiferno (Citta di Castello), Suppetie (Pieve Santo Stefano) and Massa Trabaria), donated to the Benedictine Monks of San Michele Arcangelo al Presale, the church and the monastery built as a place of prayer for his daughter. When the monastery was finally abandoned by the Benedictine Monks it was offered to San Francesco who accepted it for the Franciscan Friars. Some years later San Antonio da Padova stayed in this retreat whilst journeying to Montescasale. The Oratory of Saint Anthony (which now lies beneath the church) dates back to the first half of the 18th century and it preserves the simple bed where Saint Anthony of Padova slept.